製品の概要

  • 製品名Anti-JIP3 antibody
    JIP3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to JIP3
  • 特異性This antibody is expected to recognise both human isoforms of this protein.
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Cow, Human
  • 免疫原

    Synthetic peptide:

    MEIQMDEGGGVV

    , corresponding to N terminal amino acids 2-13 of Human JIP3.

  • 特記事項GenBank Accession Number – NP_055948; NP_203750. LocusLink ID - 23162 (human); 30957 (mouse). Gene Ontology terms - vesicle-mediated transport; kinesin complex; cytoplasm; kinesin binding; MAP-kinase scaffold activity; protein kinase binding; regulation of JNK cascade.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab4545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration.
IHC-P Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interations with the JNK-signaling components and motor proteins.
  • 配列類似性Belongs to the JIP scaffold family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-jun-amino-terminal kinase-interacting protein 3 antibody
    • FLJ00027 antibody
    • Homolog of Drosophila Sunday driver 2 antibody
    • JIP-3 antibody
    • JIP3 antibody
    • JIP3_HUMAN antibody
    • JNK / Stress Activated Protein Kinase Associated Protein 1 antibody
    • JNK Interacting Protein 3 antibody
    • JNK MAP kinase scaffold protein 3 antibody
    • JNK-interacting protein 3 antibody
    • JNK/SAPK associated protein 1 antibody
    • JSAP1 antibody
    • KIAA1066 antibody
    • MAPK8IP3 antibody
    • Mitogen Activated Protein kinase 8 Interacting Protein 3 antibody
    • Mitogen-activated protein kinase 8-interacting protein 3 antibody
    • Syd antibody
    • SYD2 antibody
    see all

Anti-JIP3 antibody 画像

  • ab4545 (4µg/ml) staining of paraffin embedded Mouse Brain. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Shows axonal staining in various regions

Anti-JIP3 antibody (ab4545) 使用論文

ab4545 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Rabbit Tissue lysate - whole (heart)
Loading amount 60 µg
Specification heart
Gel Running Conditions Non-reduced Denaturing (7.5)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
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投稿 Feb 15 2012

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Thank you for your enquiry. Ab4545 is a Fast-Track antibody; Fast-Track antibodies are immunogen affinity purified and are shown by ELISA to have high titre values against their immunogen. We are currently testing them for use in Western blotting. At t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"