製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to JDP2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 114-163 (LKTQIEELKL ERQQLILMLN RHRPTCIVRT DSVRTPESEG NPLLEQLDKK) of Mouse JDP2 (NP_112149).

  • ポジティブ・コントロール
    • Mouse heart lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
  • 配列類似性
    Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
  • 翻訳後修飾
    Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Jdp2 antibody
    • JDP2_HUMAN antibody
    • Jun dimerization protein 2 antibody
    • JUNDM2 antibody
    • Progesterone receptor co-activator antibody
    see all

画像

  • Anti-JDP2 antibody (ab105736) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size : 19 kDa

プロトコール

参考文献

ab105736 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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