製品の概要

  • 製品名Anti-Jagged 2 antibody [EPR3646]
    Jagged 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3646] to Jagged 2
  • アプリケーション適用あり: ICC/IF, WB, ICCmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide corresponding to the extracellular domain of Human Jagged 2.

  • ポジティブ・コントロール
    • HeLa, HUVEC and HT-29 cell lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration. PubMed: 24901044
WB 1/1000 - 1/10000. Predicted molecular weight: 133 kDa.
ICC 1/100 - 1/250.
  • 追加情報Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 関連性Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • 細胞内局在Cell Membrane
    • 参照データベース
    • 別名
      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all

    Anti-Jagged 2 antibody [EPR3646] 画像

    • All lanes : Anti-Jagged 2 antibody [EPR3646] (ab109627) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 133 kDa

    Anti-Jagged 2 antibody [EPR3646] (ab109627) 使用論文

    This product has been referenced in:
    • Zhou J  et al. Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury. Biol Open N/A:N/A (2016). WB ; Human . Read more (PubMed: 26794609) »
    • Zhang X  et al. FADD regulates thymocyte development at the ß-selection checkpoint by modulating Notch signaling. Cell Death Dis 5:e1273 (2014). ICC/IF ; Mouse . Read more (PubMed: 24901044) »

    See all 2 Publications for this product

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    There are currently no Abreviews or Questions for ab109627.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"