Anti-ITPR3 抗体 (ab113292)
Key features and details
- Rabbit polyclonal to ITPR3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ITPR3 antibody
ITPR3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ITPR3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Guinea pig, Gorilla, Orangutan -
免疫原
Synthetic peptide corresponding to a region within amino acids 625-675 of Human ITPR3 (NP_002215.2).
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ポジティブ・コントロール
- Human Breast Carcinoma, Colon Carcinoma, Osteosarcoma, Ovarian Carcinoma, and Stomach Adenocarcinoma tissues
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 99% Tris buffered saline, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113292の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/100 - 1/500. Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
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特記事項 |
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IHC-P
1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
ターゲット情報
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機能
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. -
組織特異性
Expressed in intestinal crypt and villus epithelial cells. -
配列類似性
Belongs to the InsP3 receptor family.
Contains 5 MIR domains. -
ドメイン
The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region. -
翻訳後修飾
Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues. -
細胞内局在
Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3710 Human
- Omim: 147267 Human
- SwissProt: Q14573 Human
- Unigene: 65758 Human
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別名
- 4 antibody
- 5-trisphosphate receptor antibody
- 5-trisphosphate receptor type 3 antibody
see all
画像
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ab113292, at 1/250 dilution, staining ITPR3 in formalin-fixed, paraffin-embedded Human stomach carcinoma by Immunohistochemistry with DAB staining.
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ab113292, at 1/250 dilution, staining ITPR3 in formalin-fixed, paraffin-embedded Human stomach carcinoma by Immunohistochemistry. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab113292 は 1 報の論文で使用されています。
- Causton B et al. CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata. Am J Respir Cell Mol Biol 59:684-694 (2018). PubMed: 29958012