製品の概要

  • 製品名ITPR2 peptide

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab5842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and ITPR2, catalog ab5805. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • 4
    • 5-trisphosphate receptor
    • Inositol 1 4 5 trisphosphate receptor type 2
    • Inositol 1,4,5-trisphosphate receptor type 2
    • Inositol 145 trisphosphate receptor type 2
    • InsP3 R2
    • InsP3R2
    • IP3 R2
    • IP3 receptor
    • IP3 receptor isoform 2
    • IP3R 2
    • IP3R2
    • ITPR 2
    • Itpr2
    • ITPR2_HUMAN
    • Type 2 inositol 1
    • Type 2 inositol 1 4 5 trisphosphate receptor
    • Type 2 inositol 145 trisphosphate receptor
    • Type 2 InsP3 receptor
    see all
  • 機能Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
  • 組織特異性Isoform Short is found in skeletal muscle and heart.
  • 関連疾患Anhidrosis, isolated, with normal sweat glands
  • 配列類似性Belongs to the InsP3 receptor family.
    Contains 5 MIR domains.
  • ドメインThe receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
  • 翻訳後修飾Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt

ITPR2 peptide (ab5842) 使用論文

ab5842 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab5842.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"