製品の概要

  • 製品名Anti-ITPR2 antibody
    ITPR2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ITPR2
  • アプリケーション適用あり: ICC, IHC-Fr, ICC/IFmore details
    適用なし: WB
  • 種交差性
    交差種: Mouse, Rat, Human, Amphibians, Salamander
    交差が予測される動物種: Cow
  • 免疫原

    Synthetic peptide corresponding to Rat ITPR2 aa 317-334.
    Sequence:

    ELNPDYRDAQNEGKTVRD


    (Peptide available as ab5842)

  • ポジティブ・コントロール
    • Rat brain staining of the hippocampus, corpus collosum, and cerebellum.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab5805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC 1/100.
IHC-Fr 1/100.
ICC/IF Use at an assay dependent concentration. PubMed: 22285480
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
    • 組織特異性Isoform Short is found in skeletal muscle and heart.
    • 関連疾患Anhidrosis, isolated, with normal sweat glands
    • 配列類似性Belongs to the InsP3 receptor family.
      Contains 5 MIR domains.
    • ドメインThe receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
    • 翻訳後修飾Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
    • 細胞内局在Endoplasmic reticulum membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 4 antibody
      • 5-trisphosphate receptor antibody
      • Inositol 1 4 5 trisphosphate receptor type 2 antibody
      • Inositol 1,4,5-trisphosphate receptor type 2 antibody
      • Inositol 145 trisphosphate receptor type 2 antibody
      • InsP3 R2 antibody
      • InsP3R2 antibody
      • IP3 R2 antibody
      • IP3 receptor antibody
      • IP3 receptor isoform 2 antibody
      • IP3R 2 antibody
      • IP3R2 antibody
      • ITPR 2 antibody
      • Itpr2 antibody
      • ITPR2_HUMAN antibody
      • Type 2 inositol 1 4 5 trisphosphate receptor antibody
      • Type 2 inositol 1 antibody
      • Type 2 inositol 145 trisphosphate receptor antibody
      • Type 2 InsP3 receptor antibody
      see all

    Anti-ITPR2 antibody 画像

    • Shows immunolocalization of IP3R-II in rat brain using ab5805.

    Anti-ITPR2 antibody (ab5805) 使用論文

    This product has been referenced in:
    • Okamoto Y  et al. Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes. J Mol Cell Cardiol 52:988-97 (2012). ICC/IF ; Rat . Read more (PubMed: 22285480) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab5805.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"