製品の概要

  • 製品名Anti-ITIH1 antibody
    ITIH1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to ITIH1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human ITIH1 (NP_002206.1).

  • ポジティブ・コントロール
    • ITIH1 transfected 293T cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab70048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).

ターゲット情報

  • 機能May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
    Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
  • 配列類似性Belongs to the ITIH family.
    Contains 1 VIT domain.
    Contains 1 VWFA domain.
  • 翻訳後修飾Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
    The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • H1P antibody
    • IATIH antibody
    • IGHEP1 antibody
    • Inter alpha (globulin) inhibitor H1 antibody
    • Inter alpha (globulin) inhibitor H1 polypeptide antibody
    • Inter alpha trypsin inhibitor heavy chain 1 antibody
    • Inter alpha trypsin inhibitor heavy chain H1 antibody
    • Inter-alpha-inhibitor heavy chain 1 antibody
    • Inter-alpha-trypsin inhibitor complex component III antibody
    • Inter-alpha-trypsin inhibitor heavy chain H1 antibody
    • ITI heavy chain H1 antibody
    • ITI-HC1 antibody
    • ITIH antibody
    • ITIH1 antibody
    • ITIH1_HUMAN antibody
    • Serum-derived hyaluronan-associated protein antibody
    • SHAP antibody
    see all

Anti-ITIH1 antibody 画像

  • All lanes : Anti-ITIH1 antibody (ab70048) at 1/500 dilution

    Lane 1 : ITIH1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 102 kDa
    Observed band size : 102 kDa

Anti-ITIH1 antibody (ab70048) 使用論文

This product has been referenced in:
  • Zhang S  et al. Constitutive expression of pentraxin 3 (PTX3) protein by human amniotic membrane cells leads to formation of the heavy chain (HC)-hyaluronan (HA)-PTX3 complex. J Biol Chem 289:13531-42 (2014). Read more (PubMed: 24652286) »
  • He H  et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . Read more (PubMed: 23878196) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"