製品の概要

  • 製品名Anti-ITGB3BP antibody
    ITGB3BP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to ITGB3BP
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: MSLFASPTSS EEQKHRNGLS NEKRKKLNHP SLTESKESTT KDNDEFMMLL SKVEKLSEEI MEIMQNLSSI QALEGSRELE NLIGISCASH FLKREMQKTK , corresponding to amino acids 1-100 of Human ITGB3BP

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性ITGB3BP is a transcriptional coregulator that has both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. ITGB3BP also acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit. ITGB3BP induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization. It also acts as a component of the CENPH-CENPI centromeric complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
    • 細胞内局在Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Cytoplasm. Isoform 4: Cytoplasm. Note=Localizes in the centromeres. Isoform 3 is predominantly nuclear and weakly cytoplasmic.
    • 参照データベース
    • 別名
      • Beta 3 endonexin antibody
      • Beta3 endonexin antibody
      • Beta3 endonexin long form antibody
      • CENP R antibody
      • CENPR antibody
      • CENPR_HUMAN antibody
      • Centromere protein R antibody
      • endonexin, Beta-3 antibody
      • HSU37139 antibody
      • Integrin beta 3 binding protein (beta3-endonexin) antibody
      • Integrin beta 3 binding protein antibody
      • NRIF 3 antibody
      • NRIF3 antibody
      • Nuclear receptor interacting factor 3 antibody
      • TAP 20 antibody
      • TAP20 antibody
      see all

    Anti-ITGB3BP antibody 画像



    • Predicted band size : 20 kDa
      ITGB3BP antibody (ab57098) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    Anti-ITGB3BP antibody (ab57098) 使用論文

    ab57098 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57098.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"