製品の概要

  • 製品名Anti-Isocitrate dehydrogenase antibody
    Isocitrate dehydrogenase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Isocitrate dehydrogenase
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Full length native protein purified from porcine heart

  • ポジティブ・コントロール
    • WB: mouse tissues including spleen, kidney, lung, heart, liver and brain.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab36329 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/400 - 1/1600.
WB 1/500 - 1/2000. Detects a band of approximately 40 kDa (predicted molecular weight: 47 kDa).

ターゲット情報

  • 関連疾患Glioma
    Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
  • 配列類似性Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 翻訳後修飾Acetylation at Lys-374 dramatically reduces catalytic activity.
  • 細胞内局在Cytoplasm. Peroxisome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cytosolic NADP isocitrate dehydrogenase antibody
    • Cytosolic NADP-isocitrate dehydrogenase antibody
    • Epididymis luminal protein 216 antibody
    • Epididymis secretory protein Li 26 antibody
    • HEL-216 antibody
    • HEL-S-26 antibody
    • ICDH antibody
    • IDCD antibody
    • IDH antibody
    • IDH1 antibody
    • IDHC_HUMAN antibody
    • IDP antibody
    • IDPC antibody
    • Isocitrate dehydrogenase [NADP] cytoplasmic antibody
    • Isocitrate dehydrogenase 1 (NADP+) soluble antibody
    • NADP dependent isocitrate dehydrogenase cytosolic antibody
    • NADP dependent isocitrate dehydrogenase peroxisomal antibody
    • NADP(+)-specific ICDH antibody
    • Oxalosuccinate decarboxylase antibody
    • PICD antibody
    see all

Anti-Isocitrate dehydrogenase antibody 画像

  • Titration curve of ab36329, rabbit antibody to Isocitrate dehyrogenase (ICDH). Plates coated with 400 ng/well of native Isocitrate Dedydrogenease derived from pig heart.

Anti-Isocitrate dehydrogenase antibody (ab36329) 使用論文

This product has been referenced in:
  • Bellingham M  et al. Exposure to chemical cocktails before or after conception - the effect of timing on ovarian development. Mol Cell Endocrinol 376:156-72 (2013). IHC . Read more (PubMed: 23791816) »
  • Mancone C  et al. Proteomic analysis reveals a major role for contact inhibition in the terminal differentiation of hepatocytes. J Hepatol 52:234-43 (2010). WB ; Mouse . Read more (PubMed: 20031246) »

See all 5 Publications for this product

Product Wall

Thank you for your enquiry. I have conferred with out laboratory and it seems that we have not tested the cross reactivity with all isoforms of the antibody, so unfortunately we do not know if ab36329 is Isocitrate dehydrogenase I or not. I am...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"