製品の概要

  • 製品名
    Anti-Isocitrate dehydrogenase antibody
    Isocitrate dehydrogenase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Isocitrate dehydrogenase
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant Human Isocitrate dehydrogenase protein.

  • ポジティブ・コントロール
    • Human liver and prostate tissues; A431 and Raji whole cell lysates

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.
IHC-P Use a concentration of 10 µg/ml.

ターゲット情報

  • 関連疾患
    Glioma
    Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
  • 配列類似性
    Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 翻訳後修飾
    Acetylation at Lys-374 dramatically reduces catalytic activity.
  • 細胞内局在
    Cytoplasm. Peroxisome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cytosolic NADP isocitrate dehydrogenase antibody
    • Cytosolic NADP-isocitrate dehydrogenase antibody
    • Epididymis luminal protein 216 antibody
    • Epididymis secretory protein Li 26 antibody
    • HEL-216 antibody
    • HEL-S-26 antibody
    • ICDH antibody
    • IDCD antibody
    • IDH antibody
    • IDH1 antibody
    • IDHC_HUMAN antibody
    • IDP antibody
    • IDPC antibody
    • Isocitrate dehydrogenase (NADP(+)) 1 cytosolic antibody
    • Isocitrate dehydrogenase [NADP] cytoplasmic antibody
    • Isocitrate dehydrogenase 1 (NADP+) soluble antibody
    • NADP dependent isocitrate dehydrogenase cytosolic antibody
    • NADP dependent isocitrate dehydrogenase peroxisomal antibody
    • NADP(+)-specific ICDH antibody
    • Oxalosuccinate decarboxylase antibody
    • PICD antibody
    see all

画像

  • All lanes : Anti-Isocitrate dehydrogenase antibody (ab113232) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 46 kDa
  • Staining of Isocitrate dehydrogenase in a formalin fixed, paraffin embedded section of Human liver, using ab1113232 at a concentration of 10 µg/ml.
  • Staining of Isocitrate dehydrogenase in a formalin fixed, paraffin embedded section of Human prostate, using ab1113232 at a concentration of 10 µg/ml.

参考文献

This product has been referenced in:
  • Naseri NN  et al. Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients. PLoS One 11:e0160384 (2016). WB . Read more (PubMed: 27611087) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab113232.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録