製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to IRAK2
  • 特異性
    ab25957 recognises IRAK2 but does not cross-react with IRAK.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Synthetic peptide, corresponding to 16 C terminal amino acids of Mouse IRAK2a isoform. This sequence is common to all four isoforms.

  • ポジティブ・コントロール
    • Whole cell lysate from A-20 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 65 kDa.

ターゲット情報

  • 機能
    Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
  • 組織特異性
    Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
  • 配列類似性
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • ドメイン
    The protein kinase domain is predicted to be catalytically inactive.
  • Information by UniProt
  • 参照データベース
  • 別名
    • il1rak2 antibody
    • Interleukin 1 receptor associated kinase 2 antibody
    • Interleukin 1 receptor associated kinase like 2 antibody
    • Interleukin-1 receptor-associated kinase-like 2 antibody
    • IRAK 2 antibody
    • IRAK-2 antibody
    • Irak2 antibody
    • IRAK2_HUMAN antibody
    • MGC150550 antibody
    see all

Anti-IRAK2 antibody 画像

  • Lane 1 : Anti-IRAK2 antibody (ab25957) at 0.5 µg/ml
    Lane 2 : Anti-IRAK2 antibody (ab25957) at 1 µg/ml
    Lane 3 : Anti-IRAK2 antibody (ab25957) at 2 µg/ml

    Lane 1 : A-20 whole cell lysate
    Lane 2 : A-20 whole cell lysate
    Lane 3 : A-20 whole cell lysate


    Predicted band size : 65 kDa

プロトコール

Anti-IRAK2 antibody (ab25957) 使用論文

ab25957 has not yet been referenced specifically in any publications.

Product Wall

Application
Western blot
Loading amount
25 µg
Gel Running Conditions
Reduced Denaturing
Sample
Mouse Cell lysate - whole cell (LIVER)
Specification
LIVER
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
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投稿 Nov 10 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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