The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 56 kDa).
機能Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
組織特異性Ubiquitously expressed, with high expression in heart, brain, testis and placenta.
配列類似性Belongs to the IPK1 type 2 family.
ドメインThe EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.