Anti-IPL-1/STK13/Aurora C 抗体 (ab38298)

製品の概要

  • 製品名Anti-IPL-1/STK13/Aurora C antibody
    IPL-1/STK13/Aurora C 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IPL-1/STK13/Aurora C
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
    適用なし: IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, selected from within amino acids 1-50 of Human IPL-1/STK13/Aurora C, (N terminal region).

  • ポジティブ・コントロール
    • 293 cell lysates and HeLa cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab38298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
ELISA 1/1000.
ICC/IF 1/100 - 1/500.
  • 追加情報Is unsuitable for IP.
  • ターゲット情報

    • 機能May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis.
    • 組織特異性Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase.
    • 関連疾患Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA.
    • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
      Contains 1 protein kinase domain.
    • 細胞内局在Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AURKC antibody
      • AIE 2 antibody
      • Aie1 antibody
      • AIE2 antibody
      • AIK 3 antibody
      • AIK3 antibody
      • ARK 3 antibody
      • ARK-3 antibody
      • ARK3 antibody
      • Aur C antibody
      • AurC antibody
      • Aurkc antibody
      • AURKC_HUMAN antibody
      • aurora 3 antibody
      • Aurora C antibody
      • Aurora kinase C antibody
      • aurora related kinase 3 antibody
      • Aurora-related kinase 3 antibody
      • Aurora/Ipl1 related kinase 3 antibody
      • Aurora/Ipl1-related kinase 3 antibody
      • Aurora/Ipl1/Eg2 protein 2 antibody
      • EC 2.7.11.1 antibody
      • Serine threonine protein kinase 13 antibody
      • serine/threonine kinase 13 (aurora/IPL1 like) antibody
      • serine/threonine protein kinase aurora C antibody
      • Serine/threonine-protein kinase 13 antibody
      • Serine/threonine-protein kinase aurora-C antibody
      • SPGF5 antibody
      • STK13 antibody
      see all

    Anti-IPL-1/STK13/Aurora C antibody 画像

    • All lanes : Anti-IPL-1/STK13/Aurora C antibody (ab38298) at 1/100 dilution

      Lane 1 : 293 cell lysate expressing Flag tag
      Lane 2 : 293 cell lysate expressing Flag tagged Aurora A
      Lane 3 : 293 cell lysate expressing Flag tagged Aurora B
      Lane 4 : 293 cell lysate expressing Flag tagged Aurora C


      Predicted band size : 36 kDa
      Observed band size : 36 kDa
      Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

      This image is courtesy of Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

    • ICC/IF image of ab38298 at 1/100 dilution staining HeLa cells, expressing GFP-Aurora C, at different cellular mitotic stages.  The images show (A), the primary antibody (B), GFP fluorescence (C), DAPI nuclear staining and (D) ab38298 merged to DAPI staining.

    Anti-IPL-1/STK13/Aurora C antibody (ab38298) 使用論文

    ab38298 has not yet been referenced specifically in any publications.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"