製品の概要

  • 製品名Anti-IP3KC antibody
    IP3KC 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IP3KC
  • 特異性ab65025 detects endogenous levels of total IP3KC protein.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of human IP3KC.

  • ポジティブ・コントロール
    • HT29 cell extracts.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab65025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/10000.
WB 1/500 - 1/1000. Detects a band of approximately 90 kDa (predicted molecular weight: 75 kDa).

ターゲット情報

  • 機能Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
  • 組織特異性Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
  • 関連疾患Defects in ITPKC are a cause of Kawasaki disease (KWD) [MIM:611775]; also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries.
  • 配列類似性Belongs to the inositol phosphokinase (IPK) family.
  • 細胞内局在Nucleus. Cytoplasm. Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4 antibody
    • 5-trisphosphate 3-kinase C antibody
    • Inositol 1 antibody
    • inositol 1,4,5 trisphosphate 3 kinase C antibody
    • Inositol trisphosphate 3 kinase C antibody
    • Inositol-trisphosphate 3-kinase C antibody
    • InsP 3 kinase C antibody
    • InsP 3-kinase C antibody
    • IP3 3-kinase C antibody
    • IP3 3KC antibody
    • IP3K C antibody
    • IP3KC antibody
    • IP3KC_HUMAN antibody
    • Itpkc antibody
    see all

Anti-IP3KC antibody 画像

  • All lanes : Anti-IP3KC antibody (ab65025) at 1/500 dilution

    Lane 1 : HT29 cell extract
    Lane 2 : HT29 cell extract with immunising peptide


    Predicted band size : 75 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-IP3KC antibody (ab65025) 使用論文

ab65025 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65025.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"