製品の概要

  • 製品名
    Anti-IP10 antibody [6D4]
    IP10 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [6D4] to IP10
  • 由来種
    Mouse
  • 特異性
    The antibody reacts specifically with Human IP-10.
  • アプリケーション
    適用あり: ICC/IF, IHC-Fr, ELISA, Flow Cyt, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant Human IP10

  • ポジティブ･コントロール
    • Activated plasmacytoid dendritic cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab8098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
IHC-Fr 1/50.
ELISA Use at an assay dependent concentration.
Flow Cyt 1/50.

ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

 
WB 1/50. Detects a band of approximately 9 kDa (predicted molecular weight: 11 kDa).

ターゲット情報

  • 機能
    Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
  • 配列類似性
    Belongs to the intercrine alpha (chemokine CxC) family.
  • 翻訳後修飾
    CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
    • 別名
      • Interferon gamma induced factor MOB1, mouse, homolog of antibody
      • Interferon gamma induced protein 10 antibody
      • 10 kDa interferon gamma induced protein antibody
      • 10 kDa interferon gamma-induced protein antibody
      • C X C motif chemokine 10 antibody
      • C7 antibody
      • Chemokine (C X C motif) ligand 10 antibody
      • Chemokine CXC motif ligand 10 antibody
      • Crg 2 antibody
      • CRG2 antibody
      • CXCL10 antibody
      • CXCL10(1-73) antibody
      • CXL10_HUMAN antibody
      • Gamma IP10 antibody
      • Gamma-IP10 antibody
      • gIP 10 antibody
      • GIP10 antibody
      • IFI10 antibody
      • INP 10 antibody
      • INP10 antibody
      • Interferon activated gene 10 antibody
      • Interferon activated gene 10 antibody
      • Interferon gamma induced cell line antibody
      • Interferon inducible cytokine IP 10 antibody
      • Interferon inducible cytokine IP10 antibody
      • IP 10 antibody
      • IP-10 antibody
      • Mob 1 antibody
      • MOB1 antibody
      • Protein 10 from interferon (gamma) induced cell line antibody
      • SCYB10 antibody
      • Small inducible cytokine B10 antibody
      • Small inducible cytokine B10 precursor antibody
      • Small inducible cytokine subfamily B (Cys X Cys) member 10 antibody
      • Small inducible cytokine subfamily B CXC member 10 antibody
      • Small inducible cytokine subfamily B, member 10 antibody
      • Small-inducible cytokine B10 antibody
      see all

    画像

    • Flow Cytometry - Anti-IP10 antibody [6D4] (ab8098)
      Flow Cytometry - Anti-IP10 antibody [6D4] (ab8098)

      Detection of IP-10 in HUVEC cells. Red, black and blue line represent the isotype control, cells only and ab8098 at 20 μg/ml, respectively.

    参考文献

    This product has been referenced in:
    • Di Carlo E  et al. Mechanisms of the antitumor activity of human V?9Vd2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma. Mol Ther 21:1034-43 (2013). Human . Read more (PubMed: 23481325) »
    • Muthuswamy R  et al. NF-?B hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells. Cancer Res 72:3735-43 (2012). Read more (PubMed: 22593190) »

    See all 6 Publications for this product

    ab8098 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

    レビューを送る 質問を送る

    18 reviews or Q&A

    10
    Votes: Highest First

    Immunocytochemistry/ Immunofluorescence abreview for Anti-IP10 antibody [6D4]

     Excellent
    Abreviews
    Application
    Immunocytochemistry/ Immunofluorescence
    Sample
    Rat Cell (brain)
    Specification
    brain
    Fixative
    Paraformaldehyde
    Permeabilization
    Yes - tritonx100
    Blocking step
    BSA as blocking agent for 20 minute(s) · Concentration: 3% · Temperature: 25°C
    Read More
    abreview image
    Username

    Abcam user community

    Verified customer

    投稿 Apr 09 2013

    Inquiry: Hallo, Ich habe eine Frage zu dem oben genannten Antikröper. Ich sehe in entsprechenden KO-Mäusen ein Signal und möchte wissen, ob es sich um eine unspezifische Reaktion handelt oder ob diese Mäuse vielleicht ein nicht funk...

    Read More

    Vielen Dank für Ihre Anfrage.
    ab8098 ist ein monoklonaler Antikörper, der mit einen rekombinantem IP10 Protein voller Länge hergestellt wurde.
    Das genaue Epitop, das der Antikörper bindet wurde leider nicht "gemapped" und es deshalb unbekannt...

    Read More

    Dear Sir/Madame,

    I am trying to find MSDS information for one of your products:

    Anti-IP10 antibody [6D4] (ab8098)

    I was just windering if you could offer me any help with this.

    Best regards,

    Thank you for your enquiry regarding ab8098.

    The SDS document for sodium azide has just been attached to the on-line product datasheet and it can be downloaded from our website.

    If you need any further assistance in the future, plea...

    Read More

    vielen Dank für den Gutscheincode. Die Bestellung des Antikörpers ist heute rausgegangen. Vielleicht schaffe ich es noch in diesem Jahr, den Antikörper auszuprobieren.
    Beste Grüße und ein schönes Weihnachtsfest.

    Vielen Dank. Ich wünsche Ihnen viel Glück mit Ihrem Versuch und hoffe alles funktioniert zu Ihrer Zufriedenheit!
    Ein schönes Fest auch für Sie und kommen Sie gut ins neue Jahr.

    das Angebot klingt gut. Ich werde den Antikörper definitiv für IHC-P ausprobieren.
    Funktioniert das denn auch für das Uniklinikum, da hier immer alle Produkte zentral über die Apotheke bestellt werden und ich vermutlich Problem...

    Read More

    Ich bin nicht sicher, wie das bei Ihnen mit den Bestellungen funktioniert. Wichtig ist dass der Code nach Freischaltung bei der nächsten Bestellung mit angegeben wird. Es kann sein, dass das von der Apotheke gemacht werden kann wenn Sie den Fall mit Ih...

    Read More

    ich benötige den Antikörper für Immunhistochemische Färbungen. Ob Cryo oder Paraffinschnitte ist mir relativ egal, Hauptsache er funktioniert auf Gewebe.
    Vielen Dank und beste Grüße

    Vielen Dank für Ihre Antwort.
    Ich denke, dass der Anti-IP10 antibody [6D4] (ab8098) dann am besten für Sie geeignet wäre. Dieser fällt unter unsere Produktgarantie von sechs Monaten. Garantiert sind alle Applikationen und Spezies, die Sie auf unser...

    Read More

    Hi Abcam,

    Please see below for an email we have received from a customer;

    I would like to request a replacement for cat# Ab8098 ordered by us. The end user Dr. Andrew Stephens, went to use it and found it was empty.

    Ple...

    Read More

    Thank you for your reply.

    I have added a new vial of ab8098 to your next order:

    Just let me know if you have further questions.

    I see that you stock the following antibody:

    Anti-IP10 antibody [6D4] (ab8098)

    I would like to use this antibody to stain for mouse CXCL10 using flow cytometry.



    Your technical info states that this antibody ...

    Read More

    Thank you for contacting us.

    We got the information for mouse cross-reactivity from one of the references (PMID: 16721359) for this antibody, but haven't tested it ourselves. However, as both Flow Cytometry as well as mouse are listed as tes...

    Read More

    I am using IP-10 antibody: ab8098 and was wondering if you offered the
    peptide used to produce the antibody? And if not, then a likely
    alternative?
    Thanks,

    Thank you for your enquiry.

    The immunogen used to generate ab8098 was Recombinant Human IP10. We stock the following products that may be of interest:

    ab9810 - IP10 protein
    www.abcam.com/ab9810
    Recombinant full length pr...

    Read More

    Dear Madam, Sir,
    Cat. AB8098 was ordered on p.o. XXXX which corresponds with Abcam order XXXXX.
    Please issue the credit note asap.
    Thank you in advance.
    Kind regards,

    Thank you for your reply.
    Your credit note ID is XXXXXX.
    The credit note may be used in one of the following ways:
    (1) Redeemed against the original invoice if this hasn't already been paid.
    (2) Held on the account for use against a...

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    1-10 of 18 Abreviews or Q&A

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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