Anti-Interferon gamma 抗体 [GIF-7] (ab9808)

製品の概要

  • 製品名Anti-Interferon gamma antibody [GIF-7]
    Interferon gamma 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [GIF-7] to Interferon gamma
  • 特異性Recognizes human IFN-g. Does not react with human IFN-a.
  • アプリケーション適用あり: ELISA, Indirect ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab9808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
Indirect ELISA
WB
  • 追加情報Indirect ELISA: use at 1/1000 to 1/5000
    Western Blot: use at 1/500 to 1/2000

  • ターゲット情報

    • 機能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
    • 組織特異性Released primarily from activated T lymphocytes.
    • 関連疾患In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
    • 配列類似性Belongs to the type II (or gamma) interferon family.
    • 翻訳後修飾Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • IFG antibody
      • IFI antibody
      • IFN gamma antibody
      • IFN, immune antibody
      • IFN-gamma antibody
      • IFNG antibody
      • IFNG_HUMAN antibody
      • Immune interferon antibody
      • Interferon gamma antibody
      see all

    Anti-Interferon gamma antibody [GIF-7] 画像

    • Western blot against human interferon gamma using ab9808 at 1 µg/ml.

    Anti-Interferon gamma antibody [GIF-7] (ab9808) 使用論文

    ab9808 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. We do not have a Western blot image with molecular weight markers for this antibody. Interferon gamma precursor is 19 kD and can be expected to run on an SDS-PAGE gel at 17 - 20 kD. The Western blot band may appear broad...

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    Thank you for your enquiry. Regarding the Western blot for ab9808: Protein (interferon-gamma) loading was 200 ng per lane. Ab9808 was used at a concentration of 1 microgram/ml. Secondary antibody: anti-mouse IgG, HRP-labeled, 1:1000 Substrate: ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"