Anti-Interferon gamma 抗体 [D9D10] (FITC) (ab11417)

製品の概要

  • 製品名Anti-Interferon gamma antibody [D9D10] (FITC)
    Interferon gamma 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [D9D10] to Interferon gamma (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性ab11417 recognises both natural and recombinant human interferon gamma, binding only to the dimeric (functional) form.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human, Baboon
  • 免疫原

    Full length native protein (purified) (Human).

  • 特記事項This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab11417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: undiluted - 1/10. Use 10 µl of the suggested working dilution to label 106 cells in 100 µl.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
    • 組織特異性Released primarily from activated T lymphocytes.
    • 関連疾患In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
    • 配列類似性Belongs to the type II (or gamma) interferon family.
    • 翻訳後修飾Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • IFG antibody
      • IFI antibody
      • IFN gamma antibody
      • IFN, immune antibody
      • IFN-gamma antibody
      • IFNG antibody
      • IFNG_HUMAN antibody
      • Immune interferon antibody
      • Interferon gamma antibody
      see all

    Anti-Interferon gamma antibody [D9D10] (FITC) (ab11417) 使用論文

    ab11417 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab11417.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"