Anti-Interferon gamma 抗体 (Biotin) (ab83136)

製品の概要

  • 製品名
    Anti-Interferon gamma antibody (Biotin)
    Interferon gamma 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Interferon gamma (Biotin)
  • 標識
    Biotin
  • アプリケーション
    適用あり: ELISA, Sandwich ELISA, WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Highly pure (>98%) recombinant mouse Interferon gamma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab83136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant murine Interferon gamma.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Interferon gamma (ab9918). This biotinylated polyclonal antibody, in conjunction with recommended pair as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mIFN-gamma. Can be used as detection antibody when paired with ab9918.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 18 kDa. The detection limit for recombinant murine Interferon gamma is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

ターゲット情報

  • 機能
    Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • 組織特異性
    Released primarily from activated T lymphocytes.
  • 関連疾患
    In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
  • 配列類似性
    Belongs to the type II (or gamma) interferon family.
  • 翻訳後修飾
    Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • IFG antibody
    • IFI antibody
    • IFN gamma antibody
    • IFN, immune antibody
    • IFN-gamma antibody
    • IFNG antibody
    • IFNG_HUMAN antibody
    • Immune interferon antibody
    • Interferon gamma antibody
    see all

プロトコール

Anti-Interferon gamma antibody (Biotin) (ab83136) 使用論文

ab83136 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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