Anti-Interferon alpha 抗体 (ab24767)

製品の概要

  • 製品名Anti-Interferon alpha antibody
    Interferon alpha 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Interferon alpha
  • 特異性Recognizes chicken Interferon alpha (chIFN-alpha). The antibody cross reacts with IFN beta but does not cross react with IFN gamma. This antibody will recognize chicken IFN beta by Western blotting; it does not neutralize its activity in vitro. It does, however, neutralize the activity of IFN alpha, and thus it can be used to distinguish the two bioactivities. Presumably it recognizes an epitope that is only revealed in IFN beta following denaturation.
  • アプリケーション適用あり: ELISA, IP, WB, Functional Studiesmore details
  • 種交差性
    交差種: Chicken
  • 免疫原

    Recombinant full length protein (Chicken)

  • 特記事項


    The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
  • Concentration information loading...
  • 精製度Protein G purified
  • 一次抗体 備考The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab24767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 19 kDa.
Functional Studies Use at an assay dependent dilution.

ターゲット情報

  • 機能Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
  • 配列類似性Belongs to the alpha/beta interferon family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • IFL antibody
    • IFN alpha antibody
    • IFN alpha 1/13 antibody
    • IFN alpha 1b antibody
    • IFN alphaD antibody
    • IFN antibody
    • IFN-alpha-1/13 antibody
    • IFNA@ antibody
    • IFNA1 antibody
    • IFNA1_HUMAN antibody
    • IFNA13 antibody
    • Interferon alpha 1 antibody
    • Interferon alpha-1/13 antibody
    • Interferon alpha-D antibody
    • Interferon alpha1 antibody
    • Interferon, alpha 13 antibody
    • LeIF D antibody
    see all

Anti-Interferon alpha antibody (ab24767) 使用論文

ab24767 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.  We do not test the concentration of the specific antibody in our protein G affinity purified antibodies. The 0.5 mg/mL concentration would correspond to total Ig. However, we expect >90% of the antibody to be specific in t...

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Thank you for your inquiry. Generally with affinity purified IgG, we expect >90% specific antibody. We do not measure the specific IgG concentration for these affinity purified products, just total IgG. I hope this information is helpful.  Plea...

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Thank you for your enquiry. The situation with this antibody is that while it will recognize chicken interferon beta by Western blotting, it does not neutralize its activity in vitro. It does, however, neutralize the activity of interferon alpha, and t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"