Anti-Integrin alpha V 抗体 [13C2] (ab78613)

製品の概要

  • 製品名
    Anti-Integrin alpha V antibody [13C2]
    Integrin alpha V 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [13C2] to Integrin alpha V
  • 特異性
    ab78613 reacts with Integrin alpha V found in osteoclasts, placenta and melanoma cell lines, some endothelial cells, smooth muscle cells and fibroblasts, and weakly in platelets.
  • アプリケーション
    適用あり: IHC-Fr, Flow Cyt, Purificationmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human osteoclastoma tissue

  • ポジティブ・コントロール
    • Human tonsil.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab78613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr
Flow Cyt
Purification
  • 追加情報
    Flow Cyt: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    P: Use at an assay dependent dilution. ab78613 can be used for purification of the vitronectin receptor.

    Note: ab78613 can be used for the following studies:
    Bone resorption modulation
    Osteoclast identification
    Malignant melanoma identification (and possible treatment)


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • 配列類似性
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • antigen identified by monoclonal antibody L230 antibody
      • CD 51 antibody
      • CD51 antibody
      • DKFZp686A08142 antibody
      • Integrin alpha five antibody
      • integrin alpha V beta 3 antibody
      • Integrin alpha-5 antibody
      • integrin alpha-V antibody
      • Integrin alpha-V light chain antibody
      • integrin alphaVbeta3 antibody
      • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
      • ITAV_HUMAN antibody
      • ITGAV antibody
      • MSK 8 antibody
      • Msk8 antibody
      • Vitronectin receptor subunit alpha antibody
      • VNRA antibody
      • VTNR antibody
      see all

    画像

    • ab78613 staining Integrin alpha V in blood vessel endothelium in frozen section of human tonsil.

    参考文献

    ab78613 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab78613.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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