Anti-Integrin alpha 5 抗体 [5H10-27] (Biotin) (ab25189)

製品の概要

  • 製品名Anti-Integrin alpha 5 antibody [5H10-27] (Biotin)
    Integrin alpha 5 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [5H10-27] to Integrin alpha 5 (Biotin)
  • 標識Biotin
  • 特異性ab25189 recognises alpha 5 subunit of the integrin alpha 5 beta 1 fibronectin receptor.
  • アプリケーション適用あり: Flow Cyt, Blocking, IHC-Fr, Functional Studiesmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation of C57BL/6 x A/J F1 mast cell line MC/9 (Mouse)

  • 特記事項


    The monoclonal antibody 5H10-27 reacts with the alpha 5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells. ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
Blocking Use at an assay dependent concentration.

In vitro blocking of adhesion.

IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.

T-cell co-stimulation.

ターゲット情報

  • 機能Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
  • 配列類似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD49 antigen-like family member E antibody
    • CD49e antibody
    • Fibronectin receptor subunit alpha antibody
    • Fibronectin receptor, alpha subunit antibody
    • FNRA antibody
    • Integrin alpha 5 (fibronectin receptor alpha) antibody
    • Integrin alpha-5 antibody
    • Integrin alpha-5 light chain antibody
    • Integrin alpha-F antibody
    • Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody
    • ITA5_HUMAN antibody
    • Itga5 antibody
    • Very late activation protein 5, alpha subunit antibody
    • VLA-5 antibody
    • VLA5 antibody
    • VLA5A antibody
    see all

Anti-Integrin alpha 5 antibody [5H10-27] (Biotin) 画像

Anti-Integrin alpha 5 antibody [5H10-27] (Biotin) (ab25189) 使用論文

ab25189 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab25189.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"