製品の概要

  • 製品名
    Anti-Integrin alpha 3b antibody [54B3]
  • 製品の詳細
    Mouse monoclonal [54B3] to Integrin alpha 3b
  • 特異性
    Recognizes specifically the cytoplasmic domain of integrin subunit a3B which is present in microvascular structures in brain and heart.
  • アプリケーション
    適用あり: WB, IHC-Fr, ICCmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: a wide range of other species
  • 免疫原

    Synthetic peptide: C-TRYYQIMPKYHAVRIREEERYPPPGSTLPTKK conjugated to KLH.

  • エピトープ
    Cytoplasmic domain of a3B Integrin.
  • 特記事項


    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 一次抗体 備考
    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.
  • ポリ/モノ
    モノクローナル
  • クローン名
    54B3
  • ミエローマ
    Sp2/0
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab8988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/1000.
IHC-Fr 1/25 - 1/200.
ICC Use at an assay dependent concentration.

ターゲット情報

  • 関連性
    Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.
  • 細胞内局在
    Cell Membrane
  • 参照データベース
  • 別名
    • CD49C antibody
    • GAPB3 antibody
    • Integrin alpha-3 heavy chain antibody
    • Integrin alpha-3 light chain antibody
    • ITGA3 antibody
    • MSK18 antibody
    • VL3A antibody
    see all

参考文献

This product has been referenced in:
  • Zhang K  et al. CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development. Dev Biol 383:15-27 (2013). Read more (PubMed: 24036311) »
  • Ipenberg I  et al. Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase. J Biol Chem 288:14681-7 (2013). Read more (PubMed: 23589305) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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