Anti-Integrin alpha 3 抗体 [17C6] (FITC) (ab30488)
製品の概要
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製品名Anti-Integrin alpha 3 antibody [17C6] (FITC)
Integrin alpha 3 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [17C6] to Integrin alpha 3 (FITC)
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由来種Mouse
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標識FITC. Ex: 493nm, Em: 528nm
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特異性ab30488 recognises CD49c, a 150kD cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is expressed by most cell types including T and B lymphocytes.
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アプリケーション適用あり: Flow Cytmore details
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種交差性交差種: Human
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免疫原
Integrin alpha 3 transfected cell line
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C.
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バッファーPreservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 -
Concentration information loading... -
精製度Protein G purified
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ポリ/モノモノクローナル
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クローン名17C6
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ミエローマNS1
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アイソタイプIgG1
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab30488 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
追加情報
Flow Cyt: Use at an assay dependent dilution. Use 10µl of working dilution for 106 cells in 100ul.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
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組織特異性Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
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配列類似性Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
翻訳後修飾Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
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細胞内局在Membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 3675 Human
- Omim: 605025 Human
- SwissProt: P26006 Human
- Unigene: 265829 Human
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別名
- AA407068 antibody
- Antigen identified by monoclonal antibody J143 antibody
- CD49 antigen like family member C antibody
see all
プロトコール
参考文献
This product has been referenced in:
- Ingenito EP et al. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med 4:259-72 (2010). Read more (PubMed: 20020503) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"