Anti-Integrin alpha 3 抗体 [17C6] (FITC) (ab30488)

製品の概要

• 製品名
  Anti-Integrin alpha 3 antibody [17C6] (FITC)
  Integrin alpha 3 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [17C6] to Integrin alpha 3 (FITC)
• 標識
  FITC. Ex: 493nm, Em: 528nm
• 特異性
  ab30488 recognises CD49c, a 150kD cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is expressed by most cell types including T and B lymphocytes.
• アプリケーション
  適用あり: Flow Cytmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Integrin alpha 3 transfected cell line

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• 精製度
  Protein G purified
• ポリ/モノ
  モノクローナル
• クローン名
  17C6
• ミエローマ
  NS1
• アイソタイプ
  IgG1
• 研究分野
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cell Adhesion
  • Integrins
  • Alpha

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能
  Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
• 組織特異性
  Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
• 配列類似性
  Belongs to the integrin alpha chain family.
  Contains 7 FG-GAP repeats.
• 翻訳後修飾
  Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
• 細胞内局在
  Membrane.

• Target information above from: UniProt accession P26006 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 3675 Human
  • Omim: 605025 Human
  • SwissProt: P26006 Human
  • Unigene: 265829 Human
• 別名
  • AA407068 antibody
  • Antigen identified by monoclonal antibody J143 antibody
  • CD49 antigen like family member C antibody

  • CD49 antigen-like family member C antibody
  • CD49c antibody
  • CD49c antigen antibody
  • FLJ34631 antibody
  • FLJ34704 antibody
  • FRP 2 antibody
  • FRP-2 antibody
  • FRP2 antibody
  • Galactoprotein B3 antibody
  • GAP B3 antibody
  • GAPB3 antibody
  • Integrin alpha 3 antibody
  • Integrin alpha-3 light chain antibody
  • Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody
  • ITA3_HUMAN antibody
  • ITGA 3 antibody
  • Itga3 antibody
  • MSK18 antibody
  • VCA 2 antibody
  • VCA2 antibody
  • Very late activation protein 3 receptor alpha 3 subunit antibody
  • VL3A antibody
  • VLA 3 alpha chain antibody
  • VLA 3 subunit alpha antibody
  • VLA-3 subunit alpha antibody
  • VLA3a antibody

  see all

プロトコール

• Flow cytometry protocols