Anti-Integrin alpha 2 抗体 [DX5] (Allophycocyanin/Cy7 ®) (ab46795)

製品の概要

  • 製品名
    Anti-Integrin alpha 2 antibody [DX5] (Allophycocyanin/Cy7 ®)
    Integrin alpha 2 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [DX5] to Integrin alpha 2 (Allophycocyanin/Cy7 ®)
  • 標識
    Allophycocyanin/Cy7 ®. Ex: 650nm, Em: 774nm
  • 特異性
    ab46795 reacts with mouse CD49b, Mr 160-kDa.
  • アプリケーション
    適用あり: Flow Cytmore details
    適用なし: IHC-Fr or IHC-P
  • 種交差性
    交差種: Mouse
  • 免疫原

    RIL 2 propagated NK1.1+ cells from C57BL/6 mice. (Fusion Partner Mouse SP2/0 myeloma cell line).

  • 特記事項
    This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µl for 106 cells.
  • 追加情報
    Is unsuitable for IHC-Fr or IHC-P.
  • ターゲット情報

    • 機能
      Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
    • 配列類似性
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • ドメイン
      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BR antibody
      • CD 49b antibody
      • CD49 antigen like family member B antibody
      • CD49 antigen-like family member B antibody
      • CD49b antibody
      • CD49b antigen antibody
      • Collagen receptor antibody
      • DX5 antibody
      • Glycoprotein Ia deficiency included antibody
      • GP Ia antibody
      • GP Ia deficiency, included antibody
      • GPIa antibody
      • HPA 5 included antibody
      • HPA5 included antibody
      • Human platelet alloantigen system 5 antibody
      • Integrin alpha 2 antibody
      • Integrin alpha II antibody
      • Integrin alpha-2 antibody
      • Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody
      • ITA2_HUMAN antibody
      • ITGA2 antibody
      • Platelet alloantigen Br(a), included antibody
      • Platelet antigen Br antibody
      • Platelet glycoprotein GPIa antibody
      • Platelet glycoprotein Ia antibody
      • Platelet glycoprotein Ia/IIa antibody
      • Platelet membrane glycoprotein Ia antibody
      • Platelet receptor for collagen, deficiency of, included antibody
      • Very late activation protein 2 receptor alpha 2 subunit antibody
      • VLA 2 alpha chain antibody
      • VLA 2 antibody
      • VLA 2 subunit alpha antibody
      • VLA-2 subunit alpha antibody
      • VLA2 antibody
      • VLA2 receptor alpha 2 subunit antibody
      • VLAA2 antibody
      see all

    画像

    • FACS analysis of B6 splenocytes, doublestained with rat anti-mouse CD49b (integrin alpha 2)-APC/Cy7 (ab46795) at 0.2 µl/106 cells and CD3-FITC.

    プロトコール

    参考文献

    ab46795 has not yet been referenced specifically in any publications.

    レビューと Q&A

    Thank you for your e-mail.
    I have contacted the Lab which produce this antibody regarding your question:
    "The immunogen used to produce this antibody was RIL-2-propagated NK1.1+ cells from C57BL/6 mice, though this antibody stains the...

    Read More
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Flow Cytometry
    Sample
    Mouse Cell (whole blood)
    Specification
    whole blood
    Permeabilization
    No
    Gating Strategy
    monocyte, lymphocyte and granulocyte
    Username

    Abcam user community

    Verified customer

    投稿 May 01 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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