製品の概要

  • 製品名Anti-Integrin alpha 1 antibody [TS2/7]
    Integrin alpha 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [TS2/7] to Integrin alpha 1
  • 特異性ab34445 recognises alpha 1 integrin subunit.
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human Integrin alpha 1 subunit.

  • ポジティブ・コントロール
    • HeLa cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab34445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/25 - 1/50. Use 10µl of the suggested working dilution to label 106 cells in 100µl.



ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

ターゲット情報

  • 機能Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
  • 配列類似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • ドメインThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 49a antibody
    • CD49 antigen-like family member A antibody
    • CD49a antibody
    • CD49a antigen antibody
    • Integrin alpha-1 antibody
    • ITA1_HUMAN antibody
    • Itga 1 antibody
    • ITGA1 antibody
    • Laminin and collagen receptor antibody
    • Very late activation protein 1 antibody
    • VLA 1 antibody
    • VLA-1 antibody
    • VLA1 antibody
    see all

Anti-Integrin alpha 1 antibody [TS2/7] 画像

  • Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (ab34445).

Anti-Integrin alpha 1 antibody [TS2/7] (ab34445) 使用論文

This product has been referenced in:
  • Chen X  et al. Integrin-mediated type II TGF-ß receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest 124:3295-310 (2014). IHC-Fr, Flow Cyt ; Human . Read more (PubMed: 24983314) »

See 1 Publication for this product

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (Tumour Cells)
Specification Tumour Cells
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: RT°C
Username

Dr. Sharon Sneddon

Verified customer

投稿 Jul 11 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"