Anti-Inhibin beta C chain 抗体 [betaC clone 1] (ab73904)
製品の概要
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製品名Anti-Inhibin beta C chain antibody [betaC clone 1]
Inhibin beta C chain 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [betaC clone 1] to Inhibin beta C chain
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由来種Mouse
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特異性This antibody has been shown to recognise both monomeric and dimeric Activin (beta C) and does not cross react with BetaAf, BetaB or BetaE.
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アプリケーション適用あり: WB, IHC-P, ELISAmore details
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種交差性交差種: Rat, Human
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免疫原
Synthetic peptide corresponding to Human Inhibin beta C chain aa 318-349.
Sequence:VPTARRPLSLLYYDRDSNIVKTDIPDMVVEAC
Database link: P55103 -
ポジティブ･コントロール
- Human Liver tissue. Staining localises to hepatocytes.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.09% Sodium azide
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Concentration information loading... -
精製度Protein G purified
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特記事項（精製）purified from tissue culture supernatant
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ポリ/モノモノクローナル
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クローン名betaC clone 1
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アイソタイプIgG1
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab73904 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/5000. Predicted molecular weight: 38 kDa. | |
| IHC-P | Use at an assay dependent concentration. | |
| ELISA | Use at an assay dependent concentration. |
ターゲット情報
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機能Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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組織特異性Expressed in benign prostatic hyperplasia.
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配列類似性Belongs to the TGF-beta family.
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細胞内局在Secreted.
- Information by UniProt
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参照データベース
- Entrez Gene: 3626 Human
- Entrez Gene: 64549 Rat
- Omim: 601233 Human
- SwissProt: P55103 Human
- SwissProt: Q9WUK5 Rat
- Unigene: 632722 Human
- Unigene: 48697 Rat
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別名
- Activin beta C chain antibody
- Activin beta-C chain antibody
- IHBC antibody
see all
画像
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Inhibin beta C chain antibody [betaC clone 1] (ab73904)](http://a.abcam.com/ps/products/73/ab73904/Images/ab73904-224357-ab73904ihcp.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Inhibin beta C chain antibody [betaC clone 1] (ab73904)This image is courtesy of an Abreview submitted by Francesco Elia Marinoab73904 staining Inhibin beta C chain in human embryonal carcinoma tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with Bouin's solution and blocked; antigen retrieval was by heat mediation. Samples were incubated with primary antibody (1/1000) for 16 hours at 4°C. An undiluted HRP-conjugated anti-mouse IgG polyclonal was used as the secondary antibody.
参考文献
This product has been referenced in:
- Mellor SL et al. Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in humanprostate and evidence for formation of new activin heterodimers of beta(C)-subunit. J Clin Endocrinol Metab 85:4851-8 (2000). Read more (PubMed: 11134153) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"