Anti-Inhibin alpha 抗体, prediluted (ab74323)

製品の概要

  • 製品名Anti-Inhibin alpha antibody, prediluted
    Inhibin alpha 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Inhibin alpha, prediluted
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide from the N-terminal of human Inhibin alpha

  • ポジティブ・コントロール
    • Testis.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab74323 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration.

ターゲット情報

  • 機能Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • 組織特異性Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
  • 配列類似性Belongs to the TGF-beta family.
  • 翻訳後修飾Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • A inhibin subunit antibody
    • A inhibin subunit precursor antibody
    • AW55578 antibody
    • IHA antibody
    • inhA antibody
    • INHA_HUMAN antibody
    • Inhibin alpha chain antibody
    • Inhibin alpha chain precursor antibody
    • Inhibin alpha subunit antibody
    see all

Anti-Inhibin alpha antibody, prediluted 画像

  • Staining of formalin-fixed, paraffin-embedded human testis tissue with ab74323.
  • Anti-Inhibin alpha antibody, prediluted (ab74323) at 1/25 dilution + lysate prepared from HeLa cells

Anti-Inhibin alpha antibody, prediluted (ab74323) 使用論文

ab74323 has not yet been referenced specifically in any publications.

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