製品の概要

  • 製品名Anti-ING4 antibody [EP3804]
    ING4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP3804] to ING4
  • アプリケーション適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC or IHC-P
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • ポジティブ・コントロール
    • 293T, T47-D, Jurkat, C6, Raw264.7 and PC-12 cell lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).Can be blocked with Human ING4 peptide (ab197784).
IP 1/10 - 1/100.
  • 追加情報Is unsuitable for Flow Cyt,ICC or IHC-P.
  • ターゲット情報

    • 機能Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1).
    • 配列類似性Belongs to the ING family.
      Contains 1 PHD-type zinc finger.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Brain my036 protein antibody
      • Candidate tumor suppressor p33 ING 1 homolog antibody
      • Candidate tumor suppressor p33 ING1 homolog antibody
      • D6Wsu147e antibody
      • D6Xrf92 antibody
      • ING 1 like protein antibody
      • ING 4 antibody
      • ING1 like protein antibody
      • ING4 antibody
      • ING4_HUMAN antibody
      • Inhibitor of growth family member 4 antibody
      • Inhibitor of growth family member 4 long isoform antibody
      • Inhibitor of growth protein 4 antibody
      • MGC12557 antibody
      • my036 antibody
      • p29 ING 4 antibody
      • p29 ING4 antibody
      • p29ING4 antibody
      see all

    Anti-ING4 antibody [EP3804] 画像

    • All lanes : Anti-ING4 antibody [EP3804] (ab108621) at 1/1000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : T47-D cell lysate
      Lane 3 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 29 kDa
    • All lanes : Anti-ING4 antibody [EP3804] (ab108621) at 1/1000 dilution

      Lane 1 : C6 cell lysate
      Lane 2 : Raw264.7 cell lysate
      Lane 3 : PC-12 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 29 kDa

    Anti-ING4 antibody [EP3804] (ab108621) 使用論文

    ab108621 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108621.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"