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RabMAb

Anti-ING1 抗体 [EPR6788] (ab124893)

製品の概要

  • 製品名
    Anti-ING1 antibody [EPR6788]
    ING1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR6788] to ING1
  • アプリケーション
    適用あり: WB, Flow Cytmore details
    適用なし: ICC/IF,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human ING1. (Uniprot: Q9UK53)

  • ポジティブ・コントロール
    • HepG2 lysate, HeLa lysate, MCF-7 lysate, Jurkat lysate, C6 lysate, RAW264.7 lysate, PC-12 lysate and NIH/3T3 lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 47 kDa.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報
    Is unsuitable for ICC/IF,IHC-P or IP.
  • ターゲット情報

    • 機能
      Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
    • 組織特異性
      Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
    • 関連疾患
      Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
    • 配列類似性
      Belongs to the ING family.
      Contains 1 PHD-type zinc finger.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2610028J21Rik antibody
      • AA407184 antibody
      • AI875420 antibody
      • Growth inhibitor ING 1 antibody
      • Growth inhibitor ING1 antibody
      • Growth inhibitory protein ING 1 antibody
      • Growth inhibitory protein ING1 antibody
      • Homo sapiens growth inhibitor p33ING1 (ING1) mRNA, complete cds antibody
      • ING 1 antibody
      • Ing1 antibody
      • ING1_HUMAN antibody
      • Inhibitor of growth 1 antibody
      • Inhibitor of growth family member 1 antibody
      • Inhibitor of growth protein 1 antibody
      • mING1h antibody
      • OTTHUMP00000018703 antibody
      • OTTHUMP00000018704 antibody
      • OTTHUMP00000018705 antibody
      • OTTHUMP00000018706 antibody
      • p24ING1c antibody
      • p33 antibody
      • p33 ING1 antibody
      • p33ING1 antibody
      • p33ING1b antibody
      • p33ING1c antibody
      • p37Ing1b antibody
      • p47 antibody
      • p47ING1a antibody
      • Tumor suppressor ING 1 antibody
      • Tumor suppressor ING1 antibody
      see all

    画像

    • All lanes : Anti-ING1 antibody [EPR6788] (ab124893) at 1/1000 dilution

      Lane 1 : HepG2 lysate
      Lane 2 : HeLa lysate
      Lane 3 : MCF-7 lysate
      Lane 4 : Jurkat lysate
      Lane 5 : C6 lysate
      Lane 6 : RAW 264.7 lysate
      Lane 7 : PC-12 lysate
      Lane 8 : NIH/3T3 lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa
    • Flow Cytometric analysis of ab124893, at 1/10 dilution, staining ING1 in permeabilised NIH/3T3cells (red). Isotype control (Green).

    参考文献

    ab124893 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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