Anti-ING1 抗体 (Biotin) - Aminoterminal end (ab55883)
製品の概要
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製品名Anti-ING1 antibody (Biotin) - Aminoterminal end
ING1 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to ING1 - Aminoterminal end (Biotin)
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由来種Rabbit
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標識Biotin
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特異性ab55883 recognizes p33 ING1. It does not cross react with other members of the ING family.
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アプリケーション適用あり: WB, ELISAmore details
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種交差性交差種: Recombinant fragment
交差が予測される動物種: Mouse, Human
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免疫原
Mouse p33 ING1 N-terminal synthetic peptide conjugated to KLH.
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特記事項
Acylation of primary amine with active ester of biotin (NHS-activated d-biotin).
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.1% Sodium Azide
Constituents: Tris buffered saline -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab55883 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. | |
| ELISA | Use a concentration of 0.25 µg/ml. |
ターゲット情報
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機能Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
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組織特異性Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
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関連疾患Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
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配列類似性Belongs to the ING family.
Contains 1 PHD-type zinc finger. -
細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 3621 Human
- Entrez Gene: 26356 Mouse
- Omim: 601566 Human
- SwissProt: Q9UK53 Human
- SwissProt: Q9QXV3 Mouse
- Unigene: 46700 Human
- Unigene: 508725 Human
- Unigene: 25709 Mouse
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別名
- 2610028J21Rik antibody
- AA407184 antibody
- AI875420 antibody
see all
プロトコール
参考文献
ab55883 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"