Anti-Indoleamine 2, 3-dioxygenase 抗体 (ab106134)

製品の概要

  • 製品名
    Anti-Indoleamine 2, 3-dioxygenase antibody
    Indoleamine 2, 3-dioxygenase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Indoleamine 2, 3-dioxygenase
  • 特異性
    Does not bind to IDO2
  • アプリケーション
    適用あり: WB, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A mixture of 3 peptides derived from Rat Indoleamine 2, 3-dioxygenase: MPHSQISPAEGSRRILEEY (1-19), LFSFPGGDCDKGFFLVSLMVE (155-176), and VKPSKQKPMGGHKSEEPS (359-376), conjugated to KLH.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50. Predicted molecular weight: 45 kDa.
IHC-P 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IHC-Fr 1/50.

ターゲット情報

  • 機能
    Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
  • パスウェイ
    Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
  • 配列類似性
    Belongs to the indoleamine 2,3-dioxygenase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3-dioxygenase antibody
    • I23O1_HUMAN antibody
    • IDO 1 antibody
    • IDO antibody
    • IDO-1 antibody
    • IDO1 antibody
    • INDO antibody
    • indolamine 2,3 dioxygenase antibody
    • Indole 2 3 dioxygenase antibody
    • indoleamine 2 3 dioxygenase 1 antibody
    • indoleamine 2 3 dioxygenase antibody
    • Indoleamine 2,3-dioxygenase 1 antibody
    • Indoleamine pyrrole 2 3 dioxygenase antibody
    • Indoleamine-pyrrole 2 antibody
    see all

画像

  • Heat inducing epitope retrieval is used as pre-treatment.  Blocking of the endogenous peroxidase is necessary to avoid unspecific background staining. 

参考文献

This product has been referenced in:
  • Nagy-Grócz G  et al. The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat. Front Neurol 8:278 (2017). WB ; Rat . Read more (PubMed: 28659861) »
  • Lu X  et al. Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. PLoS One 12:e0172339 (2017). Read more (PubMed: 28212441) »

See all 6 Publications for this product

レビューと Q&A

My name is Jeremy Kasanovand I'm helping Sybille with her emails while she is out of the office.

The antibody was tested by thelab which developed this antibodyfor cross reactivity with mouse IDO in Western blot. Unfortunately we have no deta...

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Thank you for your reply.

The information the lab sent me is all we have available. There is also a reference listed on the datasheet where human and rat tissue was used:

Hill M et al. Heme oxygenase-1 inhibits rat and human breast...

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I am very pleased to hear you would like to use ab106134 in mouse and send us an image of your results.

This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview with the imag...

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Thank you very much for your interest in ab106134 and for your patience.

Unfortunately I have not been able to obtain any more information on the tissue tested in mouse and I do not want for you to have to continue to wait for a response. Read More

I am very pleased to hear you would like to accept our offer and test ab55305 and ab106134 in monkey. These codes will give you 1 free primary antibody per code before the expiration date. To redeem this offer, please submit an Abreview for each antibo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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