Anti-CLOCK antibody (ab43106)

Product name

Anti-CLOCK antibody
KAT13D / CLOCK 抗体 (9件) 一覧

Description

Mouse polyclonal to KAT13D / CLOCK

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse

Immunogen

Vector coding for a partial recombinant fusion protein, corresponding to internal sequence amino acids 400-499 of Mouse CLOCK. Target sequence used to make the antibody: ADKSQDSGSD NRINTVSLKE ALERFDHSPT PSASSRSSRK SSHTAVSDPS STPTKIPTDT STPPRQHLPA HEKMTQRRSS FSSQSINSQS VGPSLTQPAM.

ADKSQDSGSD NRINTVSLKE ALERFDHSPT PSASSRSSRK SSHTAVSDPS STPTKIPTDT STPPRQHLPA HEKMTQRRSS FSSQSINSQS VGPSLTQPAM

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Form

Liquid

Storage instructions

Store at -20°C. Stable for 12 months at -20°C

Storage buffer

Preservative: None
Constituents: 50% Glycerol, Whole serum

Purity

Whole antiserum

Primary antibody notes

This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al.PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animal's cells produce the protein, which stimulates the animal's immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Cardiac metabolism
Cardiovascular >> Blood >> Blood Pressure regulation
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Neuroscience >> Neurology process >> Metabolism
Signal Transduction >> Metabolism >> Energy Metabolism
Neuroscience >> Neurology process >> Circadian Rhythm