製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to INCA
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-NHLTTQDSQIVLPS

    , corresponding to C terminal amino acids 97-110 of Human INCA (NP_001007233.1).

  • ポジティブ・コントロール
    • Human kidney and lung lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab99280 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 15 kDa (predicted molecular weight: 12 kDa).

ターゲット情報

  • 機能
    Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 CARD domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAR17_HUMAN antibody
    • CARD 17 antibody
    • CARD17 antibody
    • Caspase 1 inhibitor antibody
    • Caspase recruitment domain containing protein 17 antibody
    • Caspase recruitment domain-containing protein 17 antibody
    • Caspase-1 inhibitor INCA antibody
    • Caspase1 inhibitor antibody
    • Inhibitory caspase recruitment domain (CARD) protein antibody
    • Inhibitory caspase recruitment domain protein antibody
    see all

画像

  • Anti-INCA antibody (ab99280) at 0.5 µg/ml + Human kidney lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 12 kDa

プロトコール

参考文献

ab99280 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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