製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to IMPDH2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chinese hamster
  • 免疫原

    Synthetic peptide:

    KEEEHDCFLEEI

    , corresponding to internal sequence amino acids 167-178 of Human IMPDH2 (NP_000875.2).

  • ポジティブ・コントロール
    • Human Skeletal Muscle lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab85702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 56 kDa).

ターゲット情報

  • 機能
    Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • 組織特異性
    IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • パスウェイ
    Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • 配列類似性
    Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • 翻訳後修飾
    The N-terminus is blocked.
  • Information by UniProt
  • 参照データベース
  • 別名
    • IMDH2_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 2 antibody
    • IMP dehydrogenase 2 antibody
    • IMP oxireductase 2 antibody
    • IMPD 2 antibody
    • IMPD2 antibody
    • IMPDH 2 antibody
    • IMPDH II antibody
    • IMPDH-II antibody
    • Impdh2 antibody
    • Inosine 5' monophosphate dehydrogenase 2 antibody
    • Inosine 5' phosphate dehydrogenase 2 antibody
    • Inosine monophosphate dehydrogenase type II antibody
    • Inosine-5''-monophosphate dehydrogenase 2 antibody
    see all

画像

  • Anti-IMPDH2 antibody (ab85702) at 1 µg/ml + Human Skeletal Muscle lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 56 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab85702 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab85702.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録