製品の概要

  • 製品名Anti-IMPDH1 antibody
    IMPDH1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IMPDH1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 83-113 of Human IMPDH1 (NP_001136045.1, NP_899066.1, NP_001096075.1).

  • ポジティブ・コントロール
    • HL60 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab123647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 55 kDa.

ターゲット情報

  • 機能Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • 組織特異性IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • パスウェイPurine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • 関連疾患Defects in IMPDH1 are the cause of retinitis pigmentosa type 10 (RP10) [MIM:180105]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP10 inheritance is autosomal dominant.
  • 配列類似性Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • IMDH1_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 1 antibody
    • IMP dehydrogenase 1 antibody
    • IMPD 1 antibody
    • IMPD antibody
    • IMPD1 antibody
    • IMPDH 1 antibody
    • IMPDH I antibody
    • IMPDH-I antibody
    • Impdh1 antibody
    • Inosine 5' monophosphate dehydrogenase 1 antibody
    • Inosine monophosphate dehydrogenase 1 antibody
    • Inosine-5''-monophosphate dehydrogenase 1 antibody
    • LCA11 antibody
    • RP10 antibody
    • sWSS2608 antibody
    see all

Anti-IMPDH1 antibody 画像

  • Anti-IMPDH1 antibody (ab123647) at 1/100 dilution + HL60 cell line lysate at 35 µg

    Predicted band size : 55 kDa

Anti-IMPDH1 antibody (ab123647) 使用論文

ab123647 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab123647.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"