製品の概要

  • 製品名Anti-IMP3 antibody
    IMP3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IMP3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 161-210 (QQNPSPQLRG RRGPGQRGSS RQASPGSVSK QKPCDLPLRL LVPTQFVGAI) of Mouse IMP3 (NP_076159).

  • ポジティブ・コントロール
    • Mouse Kidney lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111385 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能RNA-binding protein that act as a regulator of mRNA translation and stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binds to sequences in the 3'-UTR of CD44 mRNA.
  • 組織特異性Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.
  • 配列類似性Belongs to the RRM IMP/VICKZ family.
    Contains 4 KH domains.
    Contains 2 RRM (RNA recognition motif) domains.
  • ドメインThe third and fourth KH domains are important for binding to the untranslated region (UTR) of target mRNA.
  • 細胞内局在Nucleus. Cytoplasm. Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Localized at the connecting piece and the tail of the spermatozoa. Colocalized with CD44 mRNA in RNP granules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cancer/testis antigen 98 antibody
    • CT98 antibody
    • DKFZp686F1078 antibody
    • hKOC antibody
    • IF2B3_HUMAN antibody
    • IGF II mRNA binding protein 3 antibody
    • IGF-II mRNA-binding protein 3 antibody
    • IGF2 mRNA binding protein 3 antibody
    • IGF2 mRNA-binding protein 3 antibody
    • IGF2BP3 antibody
    • IMP 3 antibody
    • IMP-3 antibody
    • Insulin like growth factor 2 mRNA binding protein 3 antibody
    • Insulin-like growth factor 2 mRNA-binding protein 3 antibody
    • KH domain containing protein overexpressed in cancer antibody
    • KH domain-containing protein overexpressed in cancer antibody
    • KOC 1 antibody
    • KOC1 antibody
    • VICKZ 3 antibody
    • VICKZ family member 3 antibody
    • VICKZ3 antibody
    see all

Anti-IMP3 antibody 画像

  • Anti-IMP3 antibody (ab111385) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 64 kDa

Anti-IMP3 antibody (ab111385) 使用論文

ab111385 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"