製品の概要

  • 製品名Anti-IL6R antibody
    IL6R 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL6R
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-468 of Human IL6R (NP_000556.1).

  • ポジティブ・コントロール
    • HeLa cell lysates. Transfected 293T cell line.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab103798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 51 kDa.

ターゲット情報

  • 機能Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
    Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
  • 組織特異性Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
    Contains 1 fibronectin type-III domain.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • ドメインThe two fibronectin type-III-like domains, contained in the N-terminal part, form together a cytokine-binding domain.
    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
  • 翻訳後修飾A short soluble form may also be released from the membrane by proteolysis.
  • 細胞内局在Secreted and Basolateral cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 126 antibody
    • CD126 antibody
    • CD126 antigen antibody
    • gp80 antibody
    • IL 6R 1 antibody
    • IL 6R alpha antibody
    • IL 6R antibody
    • IL-6 receptor alpha chain antibody
    • IL-6 receptor subunit alpha antibody
    • IL-6R 1 antibody
    • IL-6R subunit alpha antibody
    • IL-6R-alpha antibody
    • IL-6RA antibody
    • IL6Q antibody
    • Il6r antibody
    • IL6RA antibody
    • IL6RA_HUMAN antibody
    • IL6RQ antibody
    • Interleukin 6 receptor antibody
    • interleukin 6 receptor, alpha antibody
    • Interleukin-6 receptor subunit alpha antibody
    • Membrane glycoprotein 80 antibody
    • MGC30256 antibody
    see all

Anti-IL6R antibody 画像

  • Anti-IL6R antibody (ab103798) at 5 µg/ml + HeLa cell lysate at 50 µg

    Predicted band size : 51 kDa
  • All lanes : Anti-IL6R antibody (ab103798) at 5 µg/ml

    Lane 1 : IL6R transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 51 kDa

Anti-IL6R antibody (ab103798) 使用論文

This product has been referenced in:
  • Naqvi AR  et al. MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immun N/A:N/A (2013). Read more (PubMed: 24062196) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab103798.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"