Anti-IL6 抗体 [MP5-32C11] (ab7376)

製品の概要

  • 製品名Anti-IL6 antibody [MP5-32C11]
    IL6 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [MP5-32C11] to IL6
  • 特異性Specifically neutralises mouse IL-6.
  • アプリケーション適用あり: IHC-Fr, Neutralisingmore details
  • 種交差性
    交差種: Mouse
    非交差種: Rat, Human

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab7376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr
Neutralising
  • 追加情報Neutralisation of mouse IL-6
    This antibody is useful in immunochemical investigations of murine IL-6 in structural studies and for quantitative/qualitative immunochemical detection methods.
  • ターゲット情報

    • 機能Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
    • 関連疾患Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
      Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.
    • 配列類似性Belongs to the IL-6 superfamily.
    • 翻訳後修飾N- and O-glycosylated.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Interleukin BSF 2 antibody
      • B cell differentiation factor antibody
      • B cell stimulatory factor 2 antibody
      • B-cell stimulatory factor 2 antibody
      • BSF 2 antibody
      • BSF-2 antibody
      • BSF2 antibody
      • CDF antibody
      • CTL differentiation factor antibody
      • Hepatocyte stimulatory factor antibody
      • HGF antibody
      • HSF antibody
      • Hybridoma growth factor antibody
      • Hybridoma growth factor Interferon beta-2 antibody
      • IFN-beta-2 antibody
      • IFNB2 antibody
      • IL 6 antibody
      • IL-6 antibody
      • IL6 antibody
      • IL6_HUMAN antibody
      • Interferon beta 2 antibody
      • Interferon beta-2 antibody
      • Interleukin 6 antibody
      • Interleukin 6 (interferon beta 2) antibody
      • Interleukin BSF 2 antibody
      • Interleukin-6 antibody
      see all

    Anti-IL6 antibody [MP5-32C11] (ab7376) 使用論文

    ab7376 has not yet been referenced specifically in any publications.

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    Thank you for the details that you have provided. This is the first complaint that we have had concerning this antibody and as a previous vial batch worked well for you, my hunch is that perhaps this vial had gone off during the shipping process. I wil...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"