製品の概要

  • 製品名Anti-IL4 antibody
    IL4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL4
  • アプリケーション適用あり: WB, ELISA, Neutralisingmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Highly pure (>98%) recombinant mIL-4 (mouse Interleukin-4)

製品の特性

  • 製品の状態Lyophilised:Reconstitute with 200µl of sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPBS, pH 7.4, no preservative, sterile filtered
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプunknown
  • 軽鎖の種類unknown
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab9728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
Neutralising
  • 追加情報Neutralization:To yield one-half maximal inhibition [ND50] of the biological activity of mIL-4 (7.5 ng/ml), a concentration of 0.25 - 0.4 µg/ml of this antibody is required.

    ELISA:To detect mIL-4 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant mIL-4.

    Western Blot:To detect mIL-4 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-4 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
  • ターゲット情報

    • 機能Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
    • 関連疾患Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
    • 配列類似性Belongs to the IL-4/IL-13 family.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B cell growth factor 1 antibody
      • B cell IgG differentiation factor antibody
      • B Cell Stimulatory Factor 1 antibody
      • B-cell stimulatory factor 1 antibody
      • BCGF 1 antibody
      • BCGF1 antibody
      • Binetrakin antibody
      • BSF-1 antibody
      • BSF1 antibody
      • IGG1 induction factor antibody
      • IL 4 antibody
      • IL-4 antibody
      • IL4 antibody
      • IL4_HUMAN antibody
      • Il4e12 antibody
      • Interleukin 4 antibody
      • Interleukin 4 variant 2 antibody
      • Interleukin 4, isoform 1 antibody
      • Interleukin-4 antibody
      • Lymphocyte stimulatory factor 1 antibody
      • MGC79402 antibody
      • Pitrakinra antibody
      see all

    Anti-IL4 antibody (ab9728) 使用論文

    ab9728 has not yet been referenced specifically in any publications.

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    The molecular weight of Murine IL-4 is ~13.5kDa.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"