The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報Flow Cyt: Use 0.25µg for 105-8 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
配列類似性Belongs to the type I cytokine receptor family. Type 4 subfamily. Contains 2 fibronectin type-III domains.
ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
Flow cytometry image showing surface staining of normal human peripheral blood cells with ab93509 at 0.25ug per 105 cells in 100µl. Appropriate isotype controls were used (open histogram). Cells in the monocyte population were used for analysis.