製品の概要

  • 製品名
    Anti-IL36RN antibody [MM0384-2J30]
    IL36RN 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MM0384-2J30] to IL36RN
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length Human IL1F5 protein.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
  • ポリ/モノ
    モノクローナル
  • クローン名
    MM0384-2J30
  • アイソタイプ
    IgG2
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab90931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 17 kDa.

ターゲット情報

  • 機能
    Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
  • 組織特異性
    Predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Detected also in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin.
  • 関連疾患
    Defects in IL36RN are the cause of psoriasis generalized pustular (PSORP) [MIM:614204]. PSORP is a life-threatening disease defined by repeated flares of sudden onset consisting of diffuse erythematous skin eruption characterized by rapid coverage with pustules, high-grade fever, asthenia, marked leukocytosis, and elevated serum levels of C-reactive protein.
  • 配列類似性
    Belongs to the IL-1 family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI413231 antibody
    • Family of interleukin 1 delta antibody
    • FIL1 antibody
    • FIL1 delta antibody
    • FIL1(DELTA) antibody
    • FIL1D antibody
    • Fil1delta antibody
    • I36RA_HUMAN antibody
    • IL 1 delta antibody
    • IL 1 related protein 3 antibody
    • IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody
    • Il 1h3 antibody
    • IL 1HY1 antibody
    • IL 1L1 antibody
    • IL 1ra homolog antibody
    • IL 1ra homolog; IL1F5 (Canonical product IL 1F5a) antibody
    • IL 1RP3 antibody
    • IL-1 delta antibody
    • IL-1-related protein 3 antibody
    • IL-1F5 antibody
    • IL-1HY1 antibody
    • IL-1L1 antibody
    • IL-1ra homolog 1 antibody
    • IL-1RP3 antibody
    • IL1F5 antibody
    • IL1HY1 antibody
    • IL1L1 antibody
    • IL1RP3 antibody
    • IL36RA antibody
    • IL36RN antibody
    • Interleukin 1 delta antibody
    • Interleukin 1 family member 5 (delta) antibody
    • Interleukin 1 family member 5 antibody
    • Interleukin 1 HY1 antibody
    • Interleukin 1 like protein 1 antibody
    • Interleukin 1 receptor antagonist homolog 1 antibody
    • Interleukin 36 receptor antagonist antibody
    • Interleukin-1 delta antibody
    • Interleukin-1 family member 5 antibody
    • Interleukin-1 HY1 antibody
    • Interleukin-1 receptor antagonist homolog 1 antibody
    • Interleukin-1-like protein 1 antibody
    • Interleukin-36 receptor antagonist protein antibody
    • MGC29840 antibody
    • PSORP antibody
    • RP23-176J12.6 antibody
    see all

プロトコール

参考文献

ab90931 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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