製品の概要

  • 製品名Anti-IL36RN antibody
    IL36RN 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL36RN
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse, Rabbit, Horse, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 91-140 (LGTKESKSFT FYRRDLGLTS SFESAAYPGW FLCTSPEADQ PVRLTQISED) of Rat IL1F5 (NP_001101284).

  • ポジティブ・コントロール
    • Rat brain lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 17 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
  • 組織特異性Predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Detected also in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin.
  • 関連疾患Defects in IL36RN are the cause of psoriasis generalized pustular (PSORP) [MIM:614204]. PSORP is a life-threatening disease defined by repeated flares of sudden onset consisting of diffuse erythematous skin eruption characterized by rapid coverage with pustules, high-grade fever, asthenia, marked leukocytosis, and elevated serum levels of C-reactive protein.
  • 配列類似性Belongs to the IL-1 family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI413231 antibody
    • Family of interleukin 1 delta antibody
    • FIL1 antibody
    • FIL1 delta antibody
    • FIL1(DELTA) antibody
    • FIL1D antibody
    • Fil1delta antibody
    • I36RA_HUMAN antibody
    • IL 1 delta antibody
    • IL 1 related protein 3 antibody
    • IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody
    • Il 1h3 antibody
    • IL 1HY1 antibody
    • IL 1L1 antibody
    • IL 1ra homolog antibody
    • IL 1ra homolog; IL1F5 (Canonical product IL 1F5a) antibody
    • IL 1RP3 antibody
    • IL-1 delta antibody
    • IL-1-related protein 3 antibody
    • IL-1F5 antibody
    • IL-1HY1 antibody
    • IL-1L1 antibody
    • IL-1ra homolog 1 antibody
    • IL-1RP3 antibody
    • IL1F5 antibody
    • IL1HY1 antibody
    • IL1L1 antibody
    • IL1RP3 antibody
    • IL36RA antibody
    • IL36RN antibody
    • Interleukin 1 delta antibody
    • Interleukin 1 family member 5 (delta) antibody
    • Interleukin 1 family member 5 antibody
    • Interleukin 1 HY1 antibody
    • Interleukin 1 like protein 1 antibody
    • Interleukin 1 receptor antagonist homolog 1 antibody
    • Interleukin 36 receptor antagonist antibody
    • Interleukin-1 delta antibody
    • Interleukin-1 family member 5 antibody
    • Interleukin-1 HY1 antibody
    • Interleukin-1 receptor antagonist homolog 1 antibody
    • Interleukin-1-like protein 1 antibody
    • Interleukin-36 receptor antagonist protein antibody
    • MGC29840 antibody
    • PSORP antibody
    • RP23-176J12.6 antibody
    see all

Anti-IL36RN antibody 画像

  • Anti-IL36RN antibody (ab110986) at 1 µg/ml + Rat brain lysate at 10 µg

    Predicted band size : 17 kDa

Anti-IL36RN antibody (ab110986) 使用論文

ab110986 has not yet been referenced specifically in any publications.

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