製品の概要

  • 製品名Anti-IL21 antibody
    IL21 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL21
  • 特異性Peptide sequence is < 50 % identical to other interleukins in this region and is therefore not expected to cross-react.
  • アプリケーション適用あり: ELISA, ICCmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    CDSYEKKPPKEFLERFKSLLQKMIHQHLS

    , corresponding to C terminal amino acids 118-146 of Human IL21.

  • ポジティブ・コントロール
    • Human spleen cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: 1mg/ml BSA, 140mM Sodium chloride, 10mM Potassium phosphate. pH 7.2
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab18495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/100000.
ICC 1/500.

ターゲット情報

  • 機能Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
  • 組織特異性Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.
  • 配列類似性Belongs to the IL-15/IL-21 family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CVID11 antibody
    • IL 21 antibody
    • IL-21 antibody
    • Il21 antibody
    • IL21_HUMAN antibody
    • Interleukin 21 antibody
    • Interleukin-21 antibody
    • interleukin-21 isoform antibody
    • Interleukin21 antibody
    • OTTHUMP00000164088 antibody
    • Za11 antibody
    see all

Anti-IL21 antibody (ab18495) 使用論文

ab18495 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email. These two antibodies have not been tested together in a sandwich ELISA and sensitivity information is not available. However, both do detect different regions of human IL21. We do have a general sandwich ELISA protocol which y...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"