製品の概要

  • 製品名
    Anti-IL20RB antibody [20RNTC]
    IL20RB 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [20RNTC] to IL20RB
  • 特異性
    ab95824 recognizes Mouse and Human IL20RB in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1
  • アプリケーション
    適用あり: Flow Cyt, ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant mIL20RB protein (extracellular domain)

  • ポジティブ・コントロール
    • Fixed and permeabilized A375 cells

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 1% PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    20RNTC
  • アイソタイプ
    IgG2a
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab95824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use a concentration of 1 - 10 µg/ml. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
ICC/IF Use a concentration of 1 - 10 µg/ml.
WB Use at an assay dependent concentration. PubMed: 23441190

ターゲット情報

  • 機能
    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
  • 組織特異性
    Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
  • 配列類似性
    Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DIRS1 antibody
    • Fibronectin type III domain containing 6 antibody
    • FNDC6 antibody
    • I20RB_HUMAN antibody
    • IL 20R beta antibody
    • IL 20R2 antibody
    • IL-20 receptor subunit beta antibody
    • IL-20R-beta antibody
    • IL-20R2 antibody
    • IL-20RB antibody
    • IL20RB antibody
    • Interleukin 20 receptor beta antibody
    • Interleukin 20 receptor beta chain precursor antibody
    • Interleukin 20 receptor II antibody
    • Interleukin-20 receptor subunit beta antibody
    • MGC34923 antibody
    see all

画像

  • Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 µg/ml of ab95824 (right) or Rat IgG2a ? Isotype Control Purified (left) followed by Anti-Rat IgG Biotin and then Streptavidin FITC.
  • Mouse IL-20Rb-GFP 293 transfectants stained with 0.25ug ab95824 + anti-rat IgG PE

参考文献

This product has been referenced in:
  • He B  et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . Read more (PubMed: 23441190) »
  • Hsing CH  et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 18:713-25 (2012). ICC/IF . Read more (PubMed: 22186257) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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