Anti-IL-20R2 抗体 [20RNTC] (ab95824)
Key features and details
- Rat monoclonal [20RNTC] to IL-20R2
- Suitable for: Flow Cyt, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-IL-20R2 antibody [20RNTC]
IL-20R2 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [20RNTC] to IL-20R2 -
由来種
Rat -
特異性
ab95824 recognizes Mouse and Human IL-20R2 in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1 -
アプリケーション
適用あり: Flow Cyt, ICC/IFmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment corresponding to Mouse IL-20R2 (extracellular).
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ポジティブ・コントロール
- Fixed and permeabilized A375 cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 1% PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
20RNTC -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95824の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use a concentration of 1 - 10 µg/ml.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
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ICC/IF |
Use a concentration of 1 - 10 µg/ml.
|
特記事項 |
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Flow Cyt
Use a concentration of 1 - 10 µg/ml. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ICC/IF
Use a concentration of 1 - 10 µg/ml. |
ターゲット情報
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機能
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. -
組織特異性
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. -
配列類似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 53833 Human
- Entrez Gene: 213208 Mouse
- Omim: 605621 Human
- SwissProt: Q6UXL0 Human
- Unigene: 61232 Human
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別名
- DIRS1 antibody
- Fibronectin type III domain containing 6 antibody
- FNDC6 antibody
see all
画像
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (5)
ab95824 は 5 報の論文で使用されています。
- Lu Z et al. IL-20 promotes cutaneous inflammation and peripheral itch sensation in atopic dermatitis. FASEB J 36:e22334 (2022). PubMed: 35486004
- Wang HH et al. Interleukin-24 protects against liver injury in mouse models. EBioMedicine 64:103213 (2021). PubMed: 33508745
- Weng YH et al. Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation. Front Immunol 10:968 (2019). PubMed: 31114590
- He B et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . PubMed: 23441190
- Hsing CH et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 18:713-25 (2012). ICC/IF . PubMed: 22186257