製品の概要

  • 製品名
    Anti-IL2 Receptor alpha antibody [MRC OX-39]
    IL2 Receptor alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MRC OX-39] to IL2 Receptor alpha
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Tissue, cells or virus corresponding to Rat IL2 Receptor alpha.

  • ポジティブ・コントロール
    • Rat strain Wistar Con-A Activated Thymocytes.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.25µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Receptor for interleukin-2.
  • 関連疾患
    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • 配列類似性
    Contains 2 Sushi (CCP/SCR) domains.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2 Receptor alpha antibody [MRC OX-39] 画像

  • ab111849 at 0.25 µg/10<> cells detecting CD25 in Rat strain Wistar Con-A Activated Thymocytes by Flow Cytometry. 89.9% more of the cells were stained than in the control (Mouse IgG1, kappa).

プロトコール

Anti-IL2 Receptor alpha antibody [MRC OX-39] (ab111849) 使用論文

This product has been referenced in:
  • Whiteland JL  et al. Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J Histochem Cytochem 43:313-20 (1995). Read more (PubMed: 7868861) »
  • Paterson DJ  et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 24:1281-90 (1987). Read more (PubMed: 2828930) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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