製品の概要

  • 製品名Anti-IL2 Receptor alpha antibody [B-F2]
    IL2 Receptor alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [B-F2] to IL2 Receptor alpha
  • 特異性This antibody is specific for IL2 Receptor alpha. Recognizes both soluble and membrane bound human IL2 Receptor alpha.
  • アプリケーション適用あり: ICC, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    PHA activated T cells (Human)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Receptor for interleukin-2.
  • 関連疾患Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • 配列類似性Contains 2 Sushi (CCP/SCR) domains.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2 Receptor alpha antibody [B-F2] 画像

  • Staining pattern of PHA activated lymphocytes using ab46912.

Anti-IL2 Receptor alpha antibody [B-F2] (ab46912) 使用論文

This product has been referenced in:
  • Chan WC  et al. T-cell receptor antibodies in the immunohistochemical studies of normal and malignant lymphoid cells. Cancer 62:2118-24 (1988). Read more (PubMed: 3263181) »

See 1 Publication for this product

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The lymphocytes are obtained from blood sample using Ficoll Hypaque histopaque 1077 (reference from Sigma H8889, but available from other suppliers) according with the protocol given by the supplier.
The PHA is a leucoagglutinin (ref...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"