製品の概要

  • 製品名
    Anti-IL2 Receptor alpha antibody [7D4] (FITC)
    IL2 Receptor alpha 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [7D4] to IL2 Receptor alpha (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • アプリケーション
    適用あり: IP, Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    IL-2-dependent BALB/c mouse helper T-cell clone HT-2 (Mouse)

  • エピトープ
    ab25000 reacts with an epitope between amino acids 125 and 212.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at an assay dependent concentration.
Flow Cyt Use 1µg for 106 cells. ab35774-Rat monoclonal IgM, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Receptor for interleukin-2.
  • 関連疾患
    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • 配列類似性
    Contains 2 Sushi (CCP/SCR) domains.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

参考文献

This product has been referenced in:
  • Malek TR  et al. Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci U S A 80:5694-8 (1983). Read more (PubMed: 6412230) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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