製品の概要

  • 製品名
  • 製品の詳細
    Sheep polyclonal to IL1RA
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human)

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab60978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at an assay dependent dilution. Detects bands of approximately 20 and 40 kDa (predicted molecular weight: 20 kDa). We have no information regarding the 40 kDa band.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
    • 組織特異性
      The intracellular form of IL1RN is predominantly expressed in epithelial cells.
    • 関連疾患
      Microvascular complications of diabetes 4
      Interleukin 1 receptor antagonist deficiency
    • 細胞内局在
      Cytoplasm and Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DIRA antibody
      • F630041P17Rik antibody
      • ICIL 1RA antibody
      • ICIL-1RA antibody
      • ICIL1RA antibody
      • IL-1ra antibody
      • IL-1ra3 antibody
      • IL-1RN antibody
      • IL1 inhibitor antibody
      • IL1F3 antibody
      • IL1RA antibody
      • IL1RA_HUMAN antibody
      • IL1RN (IL1F3) antibody
      • IL1RN antibody
      • Interleukin 1 receptor antagonist antibody
      • Interleukin-1 receptor antagonist protein antibody
      • Intracellular IL 1 receptor antagonist type II antibody
      • Intracellular interleukin 1 receptor antagonist (icIL 1ra) antibody
      • IRAP antibody
      • MGC10430 antibody
      • MVCD4 antibody
      • Type II interleukin 1 receptor antagonist antibody
      see all

    画像

    • Anti-IL1RA antibody (ab60978) at 5 µg/ml + Recombinant human IL-1Ra. at 0.1 µg

      Secondary
      anti-sheep IgG - HRP at 1/10000 dilution

      Predicted band size : 20 kDa
      Observed band size : 20 kDa
      Additional bands at : ~40 kDa (possible dimer).

    プロトコール

    参考文献

    ab60978 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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