製品の概要

  • 製品名Anti-IL1RA antibody
    IL1RA 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL1RA
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Macaque Monkey
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human IL1RA.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in A431 human whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab104876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 20 kDa).

ターゲット情報

  • 機能Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
  • 組織特異性The intracellular form of IL1RN is predominantly expressed in epithelial cells.
  • 関連疾患Microvascular complications of diabetes 4
    Interleukin 1 receptor antagonist deficiency
  • 細胞内局在Cytoplasm and Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DIRA antibody
    • ICIL 1RA antibody
    • ICIL-1RA antibody
    • ICIL1RA antibody
    • IL-1ra antibody
    • IL-1ra3 antibody
    • IL-1RN antibody
    • IL1 inhibitor antibody
    • IL1F3 antibody
    • IL1RA antibody
    • IL1RA_HUMAN antibody
    • IL1RN (IL1F3) antibody
    • IL1RN antibody
    • Interleukin 1 receptor antagonist antibody
    • Interleukin-1 receptor antagonist protein antibody
    • Intracellular IL 1 receptor antagonist type II antibody
    • Intracellular interleukin 1 receptor antagonist (icIL 1ra) antibody
    • IRAP antibody
    • MGC10430 antibody
    • MVCD4 antibody
    • Type II interleukin 1 receptor antagonist antibody
    see all

Anti-IL1RA antibody 画像

  • Anti-IL1RA antibody (ab104876) at 1 µg/ml + A431 (Human epithelial carcinoma cell line) Whole Cell Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 20 kDa
    Observed band size : 18 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 32 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 3 minutes

Anti-IL1RA antibody (ab104876) 使用論文

ab104876 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"